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It is possible to replace just the screen on the old tps-2000 touch panels. Getting rid of the old and going to an iPad or something else would require either the original program for the coach and then editing that or reprograming the Crestron side of the coach.
If your coach uses the touch panel for the backup camera i would suggest keeping some style of hardwired panel to reduce the potential of delay in the video feed
We have reprogramed quite a few coaches over the years